LABScreen reagents are powered by Luminex xMAP technology, a microbead platform used to deliver multiplex antibody assays. This antigen-bead based assay allows for a precise determination of antibody profiles against HLA and MICA. The proven reliability of LABScreen’s consistency, high sensitivity and robustness for PRA screening has gained rapid momentum in the transplant community. The LABScreen product line consists of color-coded microbeads coated with purified HLA Class I, Class II and MICA antigens. The beads are analyzed using Luminex xMAP multiplex technology. Single antigen assays provide a unique solution to the dilemma presented by high PRA patients. In these patients, antibody reactive to one or more dominant epitopes can mask the presence of additional antibody specificities.
These specificities can now be identified by single antigen technology.